AN INVESTIGATION OF THE EFFECTS OF CINNAMOMUM CASSIA BARK EXTRACTS ON OXIDATIVE DNA DAMAGE AND POSSIBLE CYTOTOXIC AND APOPTOTIC ACTIVITIES IN TRANSFORMED/UNTRANSFORMED CELL LINES FROM TYPE 1 DIABETIC PATIENTS, IN VITRO.

An investigation of the effects of Cinnamomum cassia bark extracts on oxidative DNA damage and possible cytotoxic and apoptotic activities in transformed/untransformed cell lines from Type 1 diabetic patients, in vitro.

It was shown that patients with Type 1 diabetes mellitus (T1DM) had increased level of oxidative DNA damage and decreased efficacy of DNA repair.These changes were implicated in the increased cancer risk in patients with diabetes mellitus.Cinnamon bark extracts have diverse biological activities including antidiabetic and anti-tumor properties.Cinn

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A Parallel Environment Designing for OWL Thinking

A huge volume of information available today is in the form of images and searching the wanted images is very difficult and highly Western Assorted time-consuming.The search may take longer periods as the search volume on the internet is very huge and also the relevance of extracted images is still not up to the mark.The technologies like ontology

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The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis

Abstract Background Low serotonergic (5-HT) activity correlates with increased impulsive-aggressive behavior, while the opposite association may apply to cognitive impulsiveness.Both types of impulsivity are associated with attention-deficit/hyperactivity disorder (ADHD), and genes of functional significance for the 5-HT system are implicated in th

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To Tatiyana Alekseevna Zimina

On 14th September, 2009, Tatiyana Alekseevna Zimina was 88 when she died.She was a recognizable scientist in biology, agro-ecology, a very active researcher, and an explorer of Sakhalin latitudes.Doctor in agricultural science, veteran of labour she worked as a head of biogeochemistry laboratory and was responsible for plant recourses of Sakhalin c

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Oncolytic Orf virus licenses NK cells via cDC1 to activate innate and adaptive antitumor mechanisms and extends survival in a murine model of late-stage ovarian cancer

Background Novel therapies are needed to improve outcomes for women diagnosed with ovarian cancer.Oncolytic viruses are multifunctional immunotherapeutic biologics that preferentially infect cancer cells and stimulate inflammation with the potential to generate antitumor immunity.Herein we describe Parapoxvirus ovis (Orf virus (OrfV)), an oncolytic

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