An investigation of the effects of Cinnamomum cassia bark extracts on oxidative DNA damage and possible cytotoxic and apoptotic activities in transformed/untransformed cell lines from Type 1 diabetic patients, in vitro.
It was shown that patients with Type 1 diabetes mellitus (T1DM) had increased level of oxidative DNA damage and decreased efficacy of DNA repair.These changes were implicated in the increased cancer risk in patients with diabetes mellitus.Cinnamon bark extracts have diverse biological activities including antidiabetic and anti-tumor properties.Cinn